Diabetic gastroparesis can affect how your body absorbs any pills you take, possibly making these pills ineffective. Nasal sprays are not affected by diabetic gastroparesis because they are absorbed through the nose.1
References: 1. Gajendran M, Sarosiek I, McCallum R. Metoclopramide nasal spray for management of symptoms of acute and recurrent diabetic gastroparesis in adults. Expert Rev Endocrinol Metab. 2021;16(2):25-35. 2. Ozsoy Y, Gungor S. Nasal route: an alternative approach for antiemetic drug delivery. Expert Opin Drug Deliv. 2011;8(11):1439-1453. 3. Parkman HP, Carlson MR, Gonyer D. Metoclopramide nasal spray is effective in symptoms of gastroparesis in diabetics compared to conventional oral tablet. Neurogastroenterol Motil. 2014;26(4):521-528. 4. Data on file. EVOKE PHARMA®.
GIMOTI is a prescription medicine used 30 minutes before meals and at bedtime for 2 to 8 weeks to relieve symptoms of slow stomach emptying in adults with diabetes. Avoid treatment with metoclopramide (all dosage forms and routes of administration) for longer than 12 weeks.
GIMOTI is not recommended for use in children under age 18.
This is a summary of important information you need to know about GIMOTI. This information does not take the place of talking with your healthcare professional about your medical condition or your treatment.
Call your healthcare professional right away if you get movements you cannot stop or control, such as lip smacking, chewing, or puckering up your mouth; frowning or scowling; sticking out your tongue; blinking and moving your eyes; shaking of your arms and legs.
Before starting GIMOTI, tell your healthcare professional about all your medical conditions, especially if you have
Also tell your healthcare professional if you are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed, or drink alcohol.
Tell your healthcare professional about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.
Speak with your healthcare professional before you start or stop any other medicines.
These are not all the possible side effects of GIMOTI. Ask your healthcare professional for medical advice about side effects.
You may report side effects related to Evoke Pharma products by calling 1-833-4-GIMOTI (1-833-444-6684) or emailing GIMOTImedinfo@evokepharma.com. If you prefer to report these to the FDA, either visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
This information should not take the place of you talking with your doctor or healthcare professional. If you have any questions about your condition, or if you would like more information about GIMOTI, talk to your doctor or pharmacist. Only you and your healthcare professional can decide if GIMOTI is right for you.
Please see complete Prescribing Information, including Boxed Warning, Medication Guide, and Instructions for Use.